International Program (DAY 1)
Both Live Streaming and On-site
*Casual lunch buffet is available on-site.
Opening Remarks
October 12th Saturday 9:00~
Room 5: 4F / meeting room 411-412
- Akira Nishiyama(Kagawa University, Kagawa, Japan)
International Sponsored Symposium 1 (On-site Presentation)
Joint program of Asia Hypertension Society Network/HOPE Asia
"High-quality blood pressure management: outline "
Sponsored by A&D Company, Limited
October 12th Saturday 9:00~11:00
Room 5: 4F / meeting room 411-412
- Chairs
- Kazuomi Kario(Jichi Medical University, Tochigi, Japan)
- Ji-Guang Wang(Shanghai Jiaotong University, Shanghai, China)
- Speakers
- Yan Li(Shanghai Jiaotong University, Shanghai, China)
Home Blood Pressure Intervention in the Community
- Naoko Tomitani(Jichi Medical University, Tochigi, Japan)
Nighttime blood pressure management: actisensitivity and circadian blood pressure variability
- Kelvin Tsoi(The Chinese University of Hong Kong, Hong Kong)
Application of AI for home BP measurements
- Apichard Sukonthasarn(Chiang Mai University, Chiang Mai, Thailand)
Air pollution and hypertension in Asia
- Yook-Chin Chia(Sunway University, Kuala Lumpur, Malaysia)
Salt Restriction in Asia
- Discussants
- Kei Asayama(Teikyo University, Tokyo, Japan)
- Jinho Shin(Hanyang University Guri Hospital, Seoul, Korea)
- Sungha Park(Yonsei University, Seoul, Korea)
- Yook-Chin Chia(Sunway University, Kuala Lumpur, Malaysia)
- Apichard Sukonthasarn(Chiang Mai University, Chiang Mai, Thailand)
JSH International Session (Oral) 1 (On-line Presentation)
October 12th Saturday 11:05~11:55
Room 5: 4F / meeting room 411-412
- Chairs
- Hiroshi Akazawa(Tokyo University, Tokyo, Japan)
- Yuuichi Akasaki(Kagoshima University, Kagoshima, Japan)
- Speakers
- Nguyen Anh Tuyet(Osaka University, Osaka, Japan)
Prediction of Hypertension using Machine Learning: Findings from STEPS Noncommunicable Disease Risk Factors Survey in Vietnam
- Chengwei Liang(Xiamen University, Xiamen, China)
Deep Learning Assists Early-Detection of Hypertension-Mediated Heart Damage on ECG Signals
- Zhe Hu(Ruijin Hospital, Shanghai Jiaotong University, Shanghai, China)
Ambulatory blood pressure in male shift workers
- Ting-Wei Kao(National Taiwan University Hospital and National Taiwan University,
Taipei, Taiwan)
Performance of Primary Aldosteronism Screening in Hypertensive Patients
- Christina Daniela Brazier(University of South Africa, Pretoria, South Africa)
The correlation between high and low doses of folic acid in pregnancy complications: a systematic review and meta-analysis
JSH International Session (Oral) 2 (On-line Presentation)
October 12th Saturday 11:55~12:45
Room 5: 4F / meeting room 411-412
- Chairs
- Kei Kamide(Osaka University, Osaka, Japan)
- Takayoshi Okubo(Teikyo University, Tokyo, Japan)
- Speakers
- Tong Feng(Southern Medical University, Guangzhou, China)
Association between weekend catch-up sleep and hypertension of the United States population from 2017 to 2020: A cross-sectional study
- Boda Zhou(Tsinghua University, Beijing, China)
Irregular pulse and cardiovascular disease findings from NHANES (1999-2018)
- Yao Xiao(Sichuan University, Sichuan, China)
Comparison of the efficacy of different treatment regimens for resistant hypertension:
A network meta-analysis
- Ming-Hsien Wu(New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan)
Discontinuation versus continuation of Renin-Angiotensin System Inhibitors in Chronic Kidney Disease Stage 3-5 patients: a Meta-Analysis
- Lu Liu(Chinese Academy of Medical Sciences and Peking Union Medical College,
Beijing, China)
The Effect of Digital Therapeutics Intervention on Improving Hypertension Management in Adults: A Meta-analysis of Randomized Controlled Trial
JSH International Session (Oral) 3 (On-line Presentation)
October 12th Saturday 12:45~13:35
Room 5: 4F / meeting room 411-412
- Chairs
- Shinji Koba(Showa University, Tokyo, Japan)
- Naohiko Anzai(Chiba University, Chiba, Japan)
- Speakers
- Huynh Van Minh(Hue University of Medicine, Hue, Vietnam)
Results of the MMM 2023 hypertension screening program in Thua Thien- Hue province
- Yu-Hsuan Lin(National Taiwan University Hospital, Taipei, Taiwan)
Enhancing Diagnostic Accuracy for Primary Aldosteronism: The Role of SUV Quantification in SPECT/CT NP-59 Adrenal Scintigraphy
- Stephane Mbouna Massin(Laboratoire PRIMA SARL, Yaoundé, Cameroon)
Reference Intervals for Serum Uric Acid in Sub-Saharan Africa Adult from a Reference Population of Cameroon
- Qing Ni(Kunming Yan an Hospital, Kunming, China)
Analysis of SCNN1G gene polymorphism in patients with primary hypertension in Kunming area
- Jing Yang(The Third People's Hospital of Chengdu, Sichuan, China)
Alleviation of the mitochondrial function impairment in doxorubicin-induced cardiomycyte toxicity by cardioprotective agents
International Sponsored Symposium 2 (On-site Presentation)
Joint program of Asia Hypertension Society Network/HOPE Asia/APCMS
"Vascular function and arterial stiffness in hypertension"
Sponsored by Fukuda Denshi Co., Ltd.
October 12th Saturday 13:40~15:40
Room 5: 4F / meeting room 411-412
- Chairs
- Satoshi Hoshide(Jichi Medical University, Tochigi, Japan)
- Yook-Chin Chia(Sunway University, Kuala Lumpur, Malaysia)
- Speakers
- Kazuomi Kario(Jichi Medical University, Tochigi, Japan )
COUPLING study
- Hao-Min Cheng(Taipei Veterans General Hospital, Taipei, Taiwan)
Development and Implementation of a Home Blood Pressure Management Service Model and Community-Based Blood Pressure Management Module
- Austin Yen-Hung Lin(National Taiwan University Hospital, Taipei, Taiwan)
Primary aldosterone and vascular disease
- Sang Min Park(Eulji University, Daejeon, Korea)
TBA
- HyunJin Kim(Hanyang University Guri Hospital, Seoul, Korea)
The role of arterial stiffness on metabolic syndrome in Korea
- Atsushi Tanaka(Saga University, Saga, Japan)
Evaluation of Vascular Function in Our Clinical Trials
- Commentators
- Hirofumi Tomiyama(Tokyo Medical University Hospital, Tokyo, Japan)
- Yusuke Ohya(University of the Ryukyus Hospital, Okinawa, Japan)
JSH International Session (Oral) 4 (On-site Presentation)
Basic/Epidemiology
October 12th Saturday 15:50~17:10
Room 5: 4F / meeting room 411-412
- Chairs
- Yasuhiro Izumiya(Osaka Metropolitan University, Osaka, Japan)
- Tetsuo Nakata(Nishimura Clinic, Kyoto, Japan)
- Speakers
- Xin Fan(Lanzhou University Second Hospital, Lanzhou, China)
TRV027 reduces blood pressure in SHR and restores ventricular hypertrophy by affecting connexin 43 pathway
- Weidong Liu(The University of Osaka, Osaka, Japan)
Elucidation of a novel mechanism for the development of MASH induced by oxidized low-density lipoprotein
- Jing Ma(Shanghai Institute of Hypertension, Shanghai, China)
Intelligent Assist Office Blood Pressures (IOBP) Versus Awake Ambulatory Monitoring and Conventional Auscultatory Office Readings in Chinese Primary Medical Institutions
- Sang-Ho Jo(Hallym University Sacred Heart Hospital, Hwaseong, Korea)
Diastolic blood pressure and long-term clinical outcome in young age: 10-year follow-up of 5,653,590 from Korean nation-wide data
- Yiqing Yang(Zhongda Hospital, Southeast University, Nanjing, China)
Alcohol drinking, red cell distribution width, and stroke: a Chinese rural population-based prospective cohort study
- Yi Li(Sixth Medical Center of Chinese PLA General Hospital, Beijing, Chine)
Association of Resting Heart Rate and Blood Pressure with Clinical Outcomes in Patients with Diabetes Mellitus
- Kaiyin Li(Cardiology, Peking University First Hospital, Beijing, China)
Association between Changes in Central Blood Pressure and Peripheral Blood Pressure with Cardiovascular Events in a Chinese Community-Based Population
- Ching-Way Chen(National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan)
Association of Lower Vitamin D Levels with Elevated Blood Pressure in Young Healthy Adults in Taiwan
JSH International Best Presenter Award Candidate Session
(On-site Presentation)
October 12th Saturday 17:20~18:55
Room 5: 4F / meeting room 411-412
- Chairs
- Masanari Kuwabara(Jichi Medical University, Tochigi, Japan)
- Takafumi Ishida(Fukushima Medical University, Fukushima, Japan)
- Speakers
- Tongshuai Guo(First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China)
The association of long-term trajectories of BMI, its variability, and metabolic syndrome: A 30-year prospective cohort study
- Sang-Ho Jo(Hallym University Sacred Heart Hospital, Hwaseong, Korea)
Angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers vs. calcium channel blockers for 12,478 young hypertensive patients under 40 in 10-year follow-up
- Chieh Huang(National Taiwan University, Taipei, Taiwan)
Exploring High Prevalence and Comorbidities of Autonomous Cortisol Secretion in Primary Aldosteronism: A Retrospective Cohort Study and Systematic Review
- Yang Wang(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Associations of ultra long-term visit-to-visit blood pressure variability since childhood with vascular aging in midlife: a 30-year prospective cohort study
- Yuxi Li(Peking University First Hospital, Beijing, China)
Assessment of renovascular hypertension using fractional flow reserve and correlation with angiography and color Doppler ultrasonography: data from FAIR-pilot trial
- Hajra Akil Gupta(National Institute For Research In Reproductive and Child Health,
Mumbai, India)
Exploring the Potential of Collectin Mediated Immunotherapy in LPS-induced Model of Pre-eclampsia
- Yu-Ching Chang(National Taiwan University Hospital, Taipei, Taiwan)
The Impact of Mineralocorticoid Receptor Antagonist Treatment versus Adrenalectomy on Cardiac Remodeling and Diastolic Function in Patients with Primary Aldosteronism
- Guo Yu(Osaka University, Osaka, Japan)
LOX-1 Potentiates Amyloid β Uptake in Microglial Cells via the Biased β-Arrestin 2 Pathway in AT1 Receptor
Award Presentation
JSH International Best Presenter Award
October 12th Saturday 19:00~19:20
Room 5: 4F / meeting room 411-412
- Presenter
- Akira Nishiyama(Kagawa University, Kagawa, Japan)
International Program (DAY 2)
On-site program only
JSH International Session (Oral) 5 (On-site Presentation)
Clinical 1
October 13th Sunday 8:10~9:30
Room 7: 4F / meeting room 413
- Chairs
- Tatsuhiko Azegami(Keio University, Tokyo, Japan)
- Takeshi Tokudome(Yokohama City University, Kanagawa, Japan)
- Speakers
- Hiroyuki Mizuno(Jichi Medical University, Tochigi, Japan)
Diagnostic Accuracy of Office Blood Pressure Measurement and Home Blood Pressure Monitoring for Hypertension Screening Among Adults
- ZhengWei Chen(National Taiwan University Hospital and National Taiwan University,
Taipei, Taiwan)
Aging Matters: Addressing the Challenges in Screening of Primary Aldosteronism in Elderly individuals
- No-Ting Lin(Fu Jen Catholic University, New Taipei City, Taiwan.)
The Relationship Between Tissue Inhibitor of Metalloproteinases-1 and Presence of KCNJ5 Mutation in Aldosterone Producing Adenoma Patients
- Jieyu Liu(Peking University, Beijing, China)
Exploring the Combined Effects of Phthalate Exposure and Physical Activity Patterns on High Blood Pressure Odds in Children
- Youngro Lee(Seoul National University, Seoul, Korea)
Feasibility of watch-based blood pressure monitoring device in daily blood pressure monitoring
- Chi Wang(Sixth Medical Center of Chinese PLA General Hospital, Beijing, Chine)
In-hospital Systolic Blood Pressure Lowering Patterns and Risk of Rehospitalization for Angina in Patients with Hypertension and Coronary Artery Disease
- Pengjie Gao(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
The correlation between neck circumference and cardiac electrical remodeling in Chinese obesity-related hypertension patients
- Jia Bo Zhu(Shanghai Jiao Tong University, Shanghai, China)
Morning-to-evening changes in home blood pressure as a predictor of fatal and nonfatal cardiovascular events
JSH International Session (Oral) 6 (On-site Presentation)
Clinical 2
October 13th Sunday 9:30~10:40
Room 7: 4F / meeting room 413
- Chairs
- Masahiro Natsuaki(Saga University, Saga, Japan)
- Yoshihiro Kokubo(National Cerebral and Cardiovascular Center Hospital, Osaka,
Japan)
- Speakers
- Yang Wang(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Association of Long-term Time in Target Range for Systolic Blood Pressure Since Childhood With Arterial Stiffness in Midlife
- Yang Wang(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Combined Effects of Child and Adult Elevated Blood Pressure on Adult Subclinical Kidney Damage and Albuminuria
- Danni Wang(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
The correlation between plasma homocysteine and morning blood pressure in patients with essential hypertension
- Suining Xu(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Neck circumference is associated with serum uric acid level in patients with pre-hypertension
- Anping Cai(Guangdong Provincial People's Hospital, Guangzhou, China)
Improved cardiovascular risk prediction using echocardiography in primary prevention for community populations with hypertension
- Yu Pan(The First Affiliated Hospital of Dalian Medical University, Dalian, China)
The impact of TyG-BMI on Right Ventricular Systolic function in Hypertension, hs-CPR may be a mediator
- Thi My Linh Nguyen(Oxford University Clinical Research unit, Ho Chi Minh,
Vietnam)
Knowledge and Practice in lifestyle modification of Hypertension patients
JSH International Session (Oral) 7 (On-site Presentation)
Clinical 3
October 13th Sunday 10:40~11:50
Room 7: 4F / meeting room 413
- Chairs
- Syuntarou Kagiyama(Fukuseikai Hospital, Fukuoka, Japan)
- Ryoji Ozono(Ozono Clinic Internal Medicine & Cardiology, Hiroshima, Japan)
- Speakers
- Wei-Lun Chang(Taipei Veterans General Hospital, Taipei, Taiwan)
Effect of telemonitoring and community pharmacy-based home blood pressure case management
- Bo-Ching Lee(Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan)
Myosteatosis and sarcopenia are linked to autonomous cortisol secretion in APA
- Yi-Yao Chang(Far Eastern Memorial Hospital, New Taipei City, Taiwan)
The Effect of Aldosterone on Vascular Dysfunction: A Reservoir-Pressure Analysis Study
- Tsae-Ni Lee(Urology, National Taiwan University Hospital, Taipei, Taiwan)
Suitability of Partial Adrenalectomy for Unilateral Primary Aldosteronism: Evaluating Success with Emphasis on Partial Success as an Optimistic Outcome
- Dae-Young Kim(Inha University, Incheon, South Korea)
Impact of home blood pressure measurement on the blood pressure control in hypertensive patients
- So Ree Kim(Korea University Anam Hospital, Seoul, Korea)
Relationship between systolic blood pressure and coronary flow velocity reserve in patients with chest symptoms and non-obstructive coronary arteries
- Ziwei Wang(The University of Osaka, Osaka, Japan)
Role of α-Synuclein in Endothelial Dysfunction and Its Implications for Age-Related Dementia
JSH International session (Poster) 1 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Kimiko Ishiguro(Toranomon Hospital, Tokyo, Japan)
- Speakers
- Po-Lung Yang(National Taiwan University Hospital, Taipei, Taiwan)
Steroid Metabolite Ratios as Predictive Biomarkers for Classical Histopathology in Primary Aldosteronism
- Beining Wang(Peking University First Hospital, Beijing, China)
Enhancing detection rate and promoting data consistency in primary aldosteronism screening: an app based on Fast Healthcare Interoperability Resources (FHIR)
- Hyemoon Chung(Kyung Hee University, Seoul, Korea)
Respiratory arousal index independently is associated with the presence of hypertension than apnea-hypopnea index in patients with obstructive sleep apnea
- Wen-Kai Chu(National Taiwan University Hospital and National Taiwan University,
Taipei, Taiwan)
Incident Obstructive Sleep Apnea in Patients with Primary Aldosteronism Following COVID-19 Infection
- Yong Hyun Park(Pusan National University Yangsan Hospital, Yangsan, Korea)
Fate of Moderate to Severe Pulmonary Hypertension in Patients with Atrial Septal Defect after Surgical Correction
- Moo-Yong Rhee(Dongguk University Ilsan Hospital, Goyang, Korea)
Single-pill combination of third-dose triple antihypertensive therapy versus standard-dose monotherapy in patients with mild to moderate hypertension
JSH International session (Poster) 2 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Shinjo Sonoda(Saga University, Saga, Japan)
- Speakers
- Li Yang(Zhejiang Hospital, Hangzhou, China)
Long–term Exposure to Particulate Matter and Cause-specific Stroke Incidence: A Cohort Study in Eastern China
- Li Yang(Zhejiang Hospital, Hangzhou, China)
The long-term cardiometabolic effects of ambient ozone pollution in a large Chinese population
- Jui-Yun Hsu(College of Public Health, National Taiwan University, Taipei, Taiwan)
Association between inflammatory biomarkers with the risk of type 2 diabetes among middle-aged adults in Taiwan: a national representative study
- Praveen Veerabhadrappa(The Pennsylvania State University, Berks, PA, USA)
Cardiovascular risk factors among university employees.
- He Zheng(South China University of Technology, Guangzhou, China)
Association of antihypertensive drug target genes with stroke subtypes: A Mendelian randomization study
- Xin Chen(Ruijin Hospital, Shanghai Jiaotong University, Shanghai, China)
May Measurement Month 2020: an analysis of blood pressure screening results from China
JSH International session (Poster) 3 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Taku Inoue(Omoromachi Medical Center, Okinawa, Japan)
- Speakers
- Mingyang Tang(Affiliated Fifth People's Hospital of Chengdu University of Traditional
Chinese Medicine, Sichuan, China)
A Study on the Effects of Blue Light on Blood Pressure and Endothelial Function in Mice
- Alok Raghav(Gachon University, Seongnam, Korea)
Exposure to endocrine disruptors organochlorine pesticides and its association with Protein kinase R like ER Kinase (PERK) in Pre-eclampsia
- Qiuwen Wu(The 2nd Afliated Hospital of Harbin Medical University, Heilongjiang,
China)
VEGFC ameliorates salt-sensitive hypertension and hypertensive nephropathy by inhibiting NLRP3 inflammasome via activating VEGFR3-AMPK dependent autophagy pathway
- Hao Li(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Perivascular adipose tissue derived-leptin promotes vascular remodelling in high-fat diet induced obestiy rat model
- Eun Yi Oh(Yonsei University, Seoul, Korea)
Involvement of endocan in vascular dysfunction in angiotensin II-induced hypertensive mice
- Xiangyuan Wang(Hunan University of Traditional Chinese Medicine, Changsha,
China)
Study on the Mechanism of Naotaifang in Improving White Matter Lesions Associated with Cerebrovascular Disease via Wnt/β-catenin Pathway
- Nanxiang Yin(Osaka University, Osaka, Japan)
Investigating Doxorubicin-Induced Senescence in Pancreatic β-Cells
JSH International session (Poster) 4 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Kenichi Goto(Kyushu University, Fukuoka, Japan)
- Speakers
- Hye Yeon Koo(Seoul National University Bundang Hospital, Seongnam, Korea)
The association between hypertension and cancer screening
- Xiyang Li(First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China)
Predictive Value of Left Atrial Global Longitudinal Strain (LAGLS) for Recurrence After Catheter Ablation in Hypertensive Patients with Atrial Fibrillation
- Xia Han(Wuhan University of Science and Technology, Wuhan, China)
Hospital-based education program to reduce salt intake in outpatients with mild-to-moderate hypertension: a pilot study
- Sania Rauf(Pir Mehr Ali Shah Arid Agriculture University Rawalpindi, Rawalpindi,
Pakistan)
Whole Exome Sequencing Reveals New Mutations in the Vasopressin Synthesis Pathway in Hypertensive Cardiovascular Disease
- Bong-Goo Yoo(Kosin University Gospel Hospital, Busan, Korea)
Central-Variant Posterior Reversible Encephalopathy Syndrome with Cerebellar Infarction related to Hypertension
JSH International session (Poster) 5 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Toshiaki Otsuka(Nippon Medical School Foundation, Tokyo, Japan)
- Speakers
- Hyunsuk Kim(Chuncheon Sacred Heart Hospital, Chuncheon, Korea)
Effects of Nursing Facility Residency on Mortality in Incident HD Patients
- Huiyun Qu(People's Hospital of Henan University, Henan Provincial People's
Hospital, Zhengzhou, China)
Analysis of clinical and biochemical characteristics and impaired renal function in patients with indeterminate saline loading test
- Huiyu Du(People's Hospital of Zhengzhou University, Henan Provincial People's
Hospital, Zhengzhou, China)
Design and validation of a scoring model for differential diagnosis of hypertensive nephropathy and IgA nephropathy in hypertension patients
- Chun Yin See(National Cheng Kung University Hospital, Tainan, Taiwan)
Seasonal Home Blood Pressure Variation is Associated with Poorer Outcomes in Patients with Chronic Kidney Disease
- Chih-Cheng Wu(National Taiwan University Hospital, Hsinchu, Taiwan)
Impact or aortic energy metrics on proteinuria in advanced CKD patients
JSH International session (Poster) 6 (On-site Poster Presentation)
October 13th Sunday 14:30~15:40
Room 7: 4F / meeting room 413
- Chairs
- Yoshio Iwashima(Kansai Medical University, Osaka, Japan)
- Speakers
- Seung Hwan Han(Gachon University Gil Hospital, Incheon, Korea)
Comparison of metabolic and inflammatory markers in non-obstructive coronary artery disease patients according to metabolic syndrome
- Tetsuari Onishi(Hyogo Prefectural Harima-Himeji General Medical Center, Hyogo,
Japan)
Association Between Estimated Salt Intake and Body Mass Index in Patients with Lifestyle-Related Diseases
- Kwang Kon Koh(Gachon University, Seongnam, Korea)
Pitavastatin Reduces Lipoprotein Levels and Improves Insulin Resistance
- Kwang Kon Koh(Gachon University, Seongnam, Korea)
Korean Survey of Cardiometabolic Syndrome 2021
- Chi Wang(Sixth Medical Center of Chinese PLA General Hospital, Beijing, Chine)
Association of Inflammation and Atherogenic Dyslipidemia with Incident Cardiometabolic Disease: A Longitudinal Cohort Study
- Kuan-Yu Hung(Taipei Medical University, Taipei, Taiwan)
Comparative Effectiveness of Dipeptidyl Peptidase-4 Inhibitors versus Sulfonylureas on Clinical Profiles as Add-on to Metformin in Type 2 Diabetes